معرفی
Hongjie Li is an Assistant Professor at the Huffington Center on Aging within Baylor College of Medicine, affiliated with the Department of Molecular and Human Genetics and Dan L Duncan Comprehensive Cancer Center. He leads the Hongjie Li Lab and serves as Graduate Faculty in multiple programs.
- Education: PhD from University of Rochester & Buck Institute for Research on Aging (2016), Postdoctoral Training at Stanford University (2020)
Research Focus: Develops multi-omics technologies (transcriptomics, epigenomics, proteomics) to study neural development, aging, and age-triggered diseases. His work examines:
- Glia-neuron interactions in brain aging
- Systemic inflammatory signals
- Gut-brain axis in aging
- Tumor initiation mechanisms in aging intestines
- Integrating fly genetics with cross-species models
Notable Contributions: Pioneered single-cell RNA sequencing in Drosophila neurons (2017 Cell, 2020 Current Biology), co-developed single-nucleus RNA-seq for the Fly Cell Atlas project (2021 eLife). His recent work (2023-2025) explores:
- Whole-organism aging features
- Tauopathy neuroprotection mechanisms
- Food odor-feeding suppression circuits
- Computational frameworks for cell communication
- Histone modulation of lifespan
Scientific Awards & Funding:
- NIH R00 Pathway to Independence Award
- CPRIT (Cancer Prevention and Research Institute of Texas)
- Ted Nash Long Life Foundation
- Welch Foundation Award
- Longevity Research Grant
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