معرفی
Hiranmoy Das is a Professor in the Department of Biomedical Sciences at Texas Tech University Health Sciences Center (TTUHSC), with prior academic appointments at The Ohio State University (Associate Professor, Internal Medicine), Case Western Reserve University (Assistant Professor, Internal Medicine), and Harvard Medical School (Instructor in Medicine).
His research spans Stem Cell Biology, Immunology, and Regenerative Medicine, with specific expertise in:
- KLF2 transcription factor signaling in bone and neural systems
- Dental pulp-derived stem cell (DPSC) therapeutics
- Mitophagy/autophagy regulation in cell differentiation
- Osteoclastogenesis and bone remodeling
- Neuro-immune interactions in disease models
Analysis of his 15 most recent publications (2022-2025) reveals a dominant focus on DPSC-mediated regenerative mechanisms, particularly their secretome's role in modulating MAPK/AKT pathways for neuroinflammation control, wound healing, and bone regeneration. Key trends include KLF2 as a central regulator of mitophagy in neural/osteogenic differentiation and polyphenol compounds (Ellagic Acid, EGCG) targeting mitochondrial functions in disease models.
Das maintains active research laboratories focused on stem cell therapeutics, with significant contributions to understanding:
- Mechanisms of DPSC in glioblastoma and stroke models
- Phytochemical regulation of osteoclast/osteoblast balance
- Neurovascular communication networks
