Hinh Ly

Hinh Ly is a Professor in the Department of Veterinary and Biomedical Sciences at the University of Minnesota, with a strong affiliation to the Institute for Molecular Virology. His research focuses on host-pathogen interactions, viral pathogenesis, and immune evasion mechanisms of emerging and high-consequence viruses, particularly arenaviruses such as Lassa and Pichinde viruses.

His research interests span virology, immunology, molecular biology, and vaccine development. He investigates how viruses like Lassa and SARS-CoV-2 manipulate host signaling pathways to evade immune responses and cause disease. His work also extends to zoonotic viruses affecting both humans and animals, including swine influenza and porcine reproductive and respiratory syndrome virus (PRRSV).

The recent publications highlight a strong trend in understanding viral immune evasion, developing antiviral screening platforms, and creating diagnostic tools for emerging pathogens like dengue and Oropuche virus. His work integrates molecular virology with translational applications in public and animal health.

Scientific Awards and Recognition:
While no specific awards are listed in the provided text, his sustained NIH and USDA funding and extensive publication record indicate significant recognition in the field.

Advising and Grants:
As Principal Investigator on multiple federally funded projects, Dr. Ly leads research on:

• Development of broadly protective vaccines for swine influenza virus
• Evaluation of viral-vectored vaccines for PRRSV
• Mechanisms of immune evasion by arenaviral nucleoproteins
• Role of Lassa virus Z protein in immune suppression

He collaborates with researchers at institutions including South Dakota State University, University of Nebraska-Lincoln, and the Midwest AViDD Center.

Labs and Research Teams:
Dr. Ly leads a research team within the Institute for Molecular Virology at the University of Minnesota, focusing on high-containment virology and molecular mechanisms of viral pathogenesis. His lab develops surrogate models for high-pathogenicity viruses and engages in antiviral drug and vaccine development.