Hester Doyle

Hester Doyle, PhD, is a Research Scientist in the Department of Rheumatology, Allergy, & Immunology at Yale School of Medicine. Her research focuses on protein modifications in autoimmune diseases, immunology, and infectious diseases. She holds a PhD from the University of Oklahoma (1998), MSc (1995), and BS (1992).

• Education:
  • PhD, University of Oklahoma, 1998
  • MSc, University of Oklahoma, 1995
  • BS, Baldwin Wallace University, 1992

Her work explores mechanisms of autoimmunity, including post-translational protein modifications affecting T cell function and antigen recognition. Key projects include studies on oxidative stress in autoimmune pathology, EGFR peptide-based cancer immunotherapy, and CD4+ T cell responses to fungal pathogens like Cryptococcus neoformans.

Publications span topics like lupus autoantigens, histone stability, and chemokine roles in host defense. Collaborations with Mark Mamula, Mei-Ling Yang, and others highlight interdisciplinary research in immunology and protein biochemistry.