معرفی
Hesper Rego is an Associate Professor in Microbial Pathogenesis at the Yale School of Medicine, affiliated with the Boyer Center for Molecular Medicine. She holds a B.S. in Physics from Caltech (2005) and a Ph.D. in Biophysics from UCSF (2011). Her postdoctoral work focused on mycobacterial phenotypic heterogeneity under Eric Rubin at Harvard. Rego's lab integrates advanced microscopy techniques with studies of mycobacterial survival strategies under antibiotic and host stress.
Education:
- B.S., Physics, California Institute of Technology, 2005
- Ph.D., Biophysics, University of California, San Francisco, 2011
- Postdoctoral Fellow, Harvard School of Public Health, 2011-2016
Research Interests: Rego's work bridges microscopy innovation and microbial pathogenesis, focusing on mycobacterial physiology. Key areas include:
- Super-resolution microscopy for live-cell imaging
- Mechanisms of phenotypic heterogeneity in Mycobacterium tuberculosis
- Cellular responses to antibiotic stress
- Cell wall synthesis and lipid trafficking
Publications: Recent work highlights discoveries in mycobacterial divisome dynamics, CTP synthase filaments, and nucleoid-associated proteins' roles in antibiotic resistance. Themes include bacterial population heterogeneity, structural biology, and host-pathogen interactions.
Awards:
- Pew Biomedical Scholar (2018)
- Searle Scholar Award (2018)
- Kingsley Award in Medical Research (2016)
Lab & Collaborations: The Rego Lab works with collaborators like Lin Shao, Chunyan Wang, and María Lara-Tejero. Research focuses on live-cell imaging and systems approaches to understand mycobacterial survival strategies. Labsites include the Boyer Center for Molecular Medicine.
