Hermann Clemens Altmeppen

Hermann Clemens Altmeppen is a researcher at the Institute of Neuropathology within the Medical Faculty of the University Medical Center Hamburg-Eppendorf (UKE). His work focuses on proteolytic processing in neurodegenerative diseases, particularly prion diseases and Alzheimer's.

• Research Focus: Neurodegeneration, Cell Biology, Infectious Diseases
• Key Grants: Werner Otto Foundation, American Creutzfeldt-Jakob Disease Foundation, CRC877 Project A12

His studies investigate how proteases like ADAM10 regulate prion protein shedding and its therapeutic implications. He has contributed to understanding extracellular vesicle biology in neurological disorders and developed transgenic models for amyloid pathology.

Notable findings include spatial immune mapping in post-COVID-19 brains and conformational analysis of α-synuclein in synucleinopathies. His work bridges molecular mechanisms with clinical heterogeneity in neurodegenerative conditions.

Scientific Awards:

• Werner Otto Foundation Research Grant
• American CJD Foundation Project Funding
• CRC877 Admission (Project A12)
• Leibniz Center Infection Scholarship
• Medical Faculty UKE Young Scientists Grant
• Werner Otto Scholarship