Hengwei Zhang

Hengwei Zhang serves as Assistant Professor in the Department of Pathology and Laboratory Medicine at the University of Rochester School of Medicine and Dentistry, where he leads research in bone biology and osteoimmunology.

His primary research interests include the role of macrophages and cellular senescence in bone healing, the impact of aging on fracture repair, and the development of bone-targeted therapies for multiple myeloma and osteoporosis. He explores molecular pathways such as TGF-β signaling and proteasome inhibition.

Analysis of his recent publications reveals a consistent focus on senescent cells in aged bone, bone-targeted drug delivery (e.g., bortezomib), and the interplay between immune cells and bone metabolism in conditions like rheumatoid arthritis and periodontitis.