Heike Heuer

Prof. Dr. Heike Heuer is a leading researcher in molecular thyroidology at the Clinic for Endocrinology, Diabetes & Metabolism, University Hospital Essen. She leads the Group Molecular Thyroidology and is affiliated with the Center for Molecular Medicine (ZMB) under the research program 'Molecular and Chemical Cell Biology'. Her work focuses on thyroid hormone transporters, brain development, and endocrine disruptors, with significant contributions to understanding and treating Allan-Herndon-Dudley Syndrome (AHDS).

Research Interests:

• Molecular mechanisms of thyroid hormone action in brain development
• Role of thyroid hormone transporters (MCT8, OATP1C1) in health and disease
• Development of therapies for MCT8 deficiency
• Impact of endocrine disruptors on thyroid function
• Thyroid hormone signaling in neurodevelopment and metabolism

Her recent publications (2018–2025) reveal a strong focus on mouse models of thyroid hormone transporter deficiencies, particularly examining neurological, metabolic, and developmental outcomes. These studies frequently explore therapeutic interventions such as Triac and gene therapy, aiming to correct neurodevelopmental impairments. Her collaborative work spans neuroscience, endocrinology, and molecular biology, with publications in high-impact journals including Nature Communications, PNAS, and Thyroid.

Scientific Awards:

• No specific awards mentioned in the provided text.

Advising and Grants:
While no explicit list of students or grants is provided, her extensive co-authorship with junior researchers (e.g., Steffen Mayerl, Boyka Markova) suggests active mentorship. She is likely involved in national and international research consortia, given the collaborative nature of her publications and affiliation with ZMB and EU/DFG-funded programs.

Labs and Teams:
She leads the 'Group Molecular Thyroidology' at the University Hospital Essen, embedded within a multidisciplinary team at the Clinic for Endocrinology, Diabetes & Metabolism. Her research is supported by core facilities at ZMB and involves collaborations across Germany and internationally.