Harris Goldstein

Dr. Harris Goldstein is Professor of Pediatrics and Microbiology & Immunology at Albert Einstein College of Medicine, where he serves as Senior Associate Dean for Scientific Affairs and holds the Charles Michael Chair in Autoimmune Diseases. He directs the Einstein-Rockefeller-CUNY Center for AIDS Research, coordinating HIV investigations across multiple institutions.

Research Focus: Goldstein's NIH-funded program develops immunotherapies for HIV cure, including CAR-T cells targeting latent reservoirs and synthetic T-cell activation strategies. His lab employs molecular, cellular, and biochemical approaches to enhance immune control of HIV, with parallel investigations on neurocognitive impacts of HIV and substance use. Current projects focus on duoCAR-T cells, TCR-targeted biologics, and combinatorial approaches for sustained ART-free remission.

Publication Trends: Goldstein's 2019-2025 publications demonstrate evolving focus on engineered immunotherapies, particularly CAR-T platforms for HIV eradication. Recent work emphasizes preclinical validation of duoCAR-T cells, SynTac immunobiologics, and humanized mouse models for cure strategies. Secondary themes include reservoir characterization, prevention monitoring, and neuropathogenesis.

Leadership: As director of the NIH-funded Einstein-Rockefeller-CUNY CFAR, Goldstein oversees collaborative HIV research involving over 150 investigators across three institutions, focused on prevention, treatment optimization, and cure strategies.