معرفی
Haribabu Arthanari, Ph.D. is an Associate Professor at the Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, with a secondary affiliation at the Department of Cancer Biology, Dana-Farber Cancer Institute. His research focuses on therapeutic targeting of protein-protein interactions (PPIs) through structure-guided approaches, utilizing NMR spectroscopy, high-throughput screening, and biophysical assays to validate disease-related interactions and identify inhibitors.
- Key Research Areas: Transcription factor interactions with the Mediator complex, translation initiation machinery in cancer, and NMR methods for studying disordered proteins ("Dark Proteome").
- Recent Trends: 2023-2025 publications highlight mitochondrial metabolism (ergothioneine/MPST), transcriptional condensate assembly, and computational drug discovery platforms.
- Techniques: NMR spectroscopy, TROSY methods, virtual screening, protein semisynthesis, biophysical and cell-based assays.
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