معرفی
A/Prof HO Han Kiat is an Associate Professor in the Department of Pharmacy and Pharmaceutical Sciences at the National University of Singapore. His research focuses on chronic liver disease progression (from fatty liver to cancer) and drug-induced liver injury mechanisms. He explores nanomaterial applications in disease modification and drug delivery, using techniques like high-throughput sequencing and preclinical collaborations with clinicians. His work bridges cancer biology and toxicology, emphasizing clinical relevance through patient sample correlations.
He teaches courses such as PR4207 Applied Pharmacokinetics & Toxicokinetics and FSC4203 Forensic Toxicology & Poisons. His lab’s vision involves developing molecular interventions for liver disorders through in vitro/vivo models. Notable interests include nanomaterial toxicity, hepatoprotective strategies, and cytokine profiles in cognitive impairment post-chemotherapy.
Recent articles highlight studies on BDNF biomarkers, gold nanoparticle vascular targeting, and therapeutic hypothermia for hepatotoxicity. His research integrates genetic polymorphism analysis (e.g., CYP7A1) with drug metabolism studies, emphasizing personalized medicine approaches.
HO’s work also addresses educational innovations in pharmacy curricula and assessment design, reflecting his dual focus on clinical research and pedagogy.
