معرفی
Associate Professor Guoping Zheng is affiliated with the Westmead Clinical School at the University of Sydney, specializing in nephrology and immunology. His research focuses on kidney fibrosis, inflammation, and the roles of macrophages, TGF-β signaling, and β-catenin in renal pathologies. He collaborates with institutions like the Norris Comprehensive Cancer Research Center (University of Southern California) on Wnt/b-catenin inhibitor studies.
Key research interests include the molecular mechanisms of kidney disease progression, particularly in chronic conditions and transplant fibrosis. He has secured grants from the National Health and Medical Research Council (NHMRC), including a Peter Doherty Fellowship (2006) and recent grants targeting β-catenin/FoxO pathways and kidney failure prevention. His work spans experimental models of kidney injury and translational therapies.
Publications highlight contributions to understanding renal fibrosis, macrophage biology, and TGF-β's dual roles in inflammation/fibrosis. Recent studies investigate therapeutic strategies like Flt3 inhibitors and engineered macrophages. His team actively supervises research projects on MMPs, E-cadherin, and β-catenin in kidney disease pathogenesis.
- Grants: Over 10 NHMRC grants since 2006, including $2.5M+ for fibrosis research.
- Students: Advises Xutong HU on AKI-to-CKD transition mechanisms.
- Labs/Teams: Collaborates with multidisciplinary groups in nephrology and immunology.
