Guido Reifenberger

Guido Reifenberger serves as an Adjunct Professor in the Department of Clinical Medicine at the University of Copenhagen, with primary email affiliation at Heinrich Heine University Düsseldorf. His academic profile centers on neuropathology and oncology research, focusing on molecular mechanisms in brain tumor pathogenesis and vascular biology.

His research interests include:

• Neuropathology
• Neuro-oncology
• Vascular Biology
• Molecular Biology
• Brain Tumor Research

Dr. Reifenberger investigates how oncometabolites like D-2-hydroxyglutarate influence glioma microenvironment dynamics, particularly endothelial cell function and blood-brain barrier integrity. His work bridges cancer metabolism and vascular pathology to identify therapeutic targets for IDH-mutant gliomas.

His 2023 publication in the Journal of Neuropathology and Experimental Neurology demonstrates how D-2-hydroxyglutarate drives endothelial proliferation and barrier disruption, revealing key mechanisms in glioma-associated vascular abnormalities. This research exemplifies his focus on metabolic dysregulation in brain tumor progression.