Guido Reifenberger

Professor Guido Reifenberger is the Director of the Institute of Neuropathology at Heinrich Heine University Düsseldorf. He specializes in molecular neurooncology, focusing on genetic and epigenetic aberrations in primary brain tumors including gliomas, meningiomas, medulloblastomas, CNS lymphomas, and brain metastases.

• Director of the Institute of Neuropathology
• Member of the German Glioma Network
• Contributor to WHO CNS tumor classification
• Leader in establishing the CNS tumor tissue bank Düsseldorf

His research integrates genome-wide and transcriptome-wide profiling to study tumor suppressor genes, proto-oncogenes, and non-coding RNA alterations. He has pioneered translational research linking genomic findings to clinical diagnostics through the German Cancer Consortium (DKTK). Key projects include:

• BMBF SysGlio Consortium (systems biology of glioma progression)
• Brain Tumor Funders Collaborative (glioblastoma survival mechanisms)
• DKTK non-coding mutation studies
• German Cancer Aid initiatives on meningiomas and brain metastases

Publications reveal a focus on glioma molecular genetics, therapy resistance mechanisms, epigenetic alterations, and diagnostic implementation. His work has significantly influenced glioblastoma classification and treatment stratification.

He collaborates with the Department of Neurosurgery at University Hospital Düsseldorf to maintain one of the world's largest brain tumor tissue banks, facilitating research on tumor heterogeneity and personalized treatment strategies.