Greg Cuny

Greg Cuny is a faculty member at the University of Houston College of Pharmacy, serving as the Professor of Medicinal Chemistry and Chair of the Department of Pharmacological and Pharmaceutical Sciences. His research focuses on synthetic medicinal chemistry, particularly in designing pharmacology probes for novel therapeutic strategies and incorporating conformationally restricted natural products into drug development.

• Education:
  • Ph.D. in Organic Chemistry, Massachusetts Institute of Technology
  • B.S. in Chemistry, Grove City College

Greg Cuny's research integrates approaches in organic synthesis, molecular modeling/docking, and structure-based design to optimize pharmacological agents. His work targets kinase inhibition, nucleotide metabolism, and host-pathogen interactions, with applications in inflammatory diseases, tuberculosis, and parasitology.

His recent publications highlight advancements in RIPK2 inhibitors, IMPDH inhibition, and synthesis of complex natural product frameworks. The work demonstrates a strong emphasis on developing chemical probes for understanding disease mechanisms and identifying potential drug candidates.

Scientific Awards:

• Joseph P. & Shirley Shipman Buckley Endowed Professor of Drug Discovery

Greg Cuny's research program is supported by grants and collaborations focused on drug discovery and medicinal chemistry. He has mentored postdoctoral researchers and graduate students in organic synthesis techniques and pharmaceutical sciences. His laboratory serves as a hub for interdisciplinary research between chemistry and pharmacology.