معرفی
Grace Mennen is a Research Fellow in Drug Discovery Biology at Monash University, specializing in G protein-coupled receptor (GPCR) pharmacology with emphasis on calcitonin and CGRP receptor families. Her work bridges molecular pharmacology and drug discovery within Monash's research ecosystem.
Research Focus: Her primary interests include biased agonism, receptor signaling mechanisms, and novel ligand development for GPCRs. Current work centers on characterizing βCGRP signaling profiles and evaluating agonists like AM833 for therapeutic applications in migraine and metabolic disorders, leveraging techniques in molecular pharmacology and receptor biochemistry.
Publication Trends: Recent work demonstrates consistent focus on receptor pharmacology through rigorous comparative analyses of novel compounds. Her 2021-2025 publications reveal progression from foundational agonist characterization (AM833) to advanced biased signaling studies (βCGRP), highlighting evolving expertise in receptor subtype specificity and therapeutic targeting.
Collaborative Network: Works within Monash's Drug Discovery Biology group alongside prominent researchers including P.M. Sexton, D. Wootten, and P. Zhao. Her publications show strong institutional collaboration with Monash Institute of Pharmaceutical Sciences, contributing to UN Sustainable Development Goals related to health innovation.
