Giampaolo Perna

Giampaolo Perna serves as Full Professor of Psychiatry at Humanitas University in Milan, where he leads the Personalized Medicine Center for Anxiety and Panic Disorders at Humanitas San Pio X. His clinical leadership extends to roles as Scientific Director of Psico Medical Care at Humanitas Medical Care, Chairman of the Department of Clinical Neurosciences at Villa San Benedetto Menni, and Chair of the World Psychiatric Association section on Personalized Psychiatry. He maintains international academic appointments as Voluntary Professor at the University of Miami and Visiting Associate Professor at Maastricht University.

His educational foundation includes:

• Scientific High School
• Degree in Medicine and Surgery
• PhD in Psychiatry and Relational Sciences
• Residentship in Psychiatry

Perna's research pioneers personalized psychiatry through biomarker integration and machine learning applications. His work focuses on physiological mechanisms in panic disorder (notably heart rate variability), comorbidity patterns between anxiety disorders and physical conditions like asthma/sinusitis, and digital mental health platforms for depression screening. He has developed affective neuroscience frameworks to translate laboratory findings into clinical protocols for anxiety and depression management.

Recent publications (2024-2025) demonstrate three convergent trends: (1) Machine learning-driven screening tools for depression in sleep clinics, (2) Clinical profiling of panic disorder's impact on respiratory conditions, and (3) Workforce mental health studies examining academic stress in medical students and burnout among clinicians. This output reflects his commitment to data-driven personalization across diagnostic, treatment, and prevention domains.

As an educator across seven institutions (including Milan, L'Aquila, Maastricht, and Miami), Perna has mentored students to degrees in Medicine/Psychology, PhDs, and psychiatry residencies globally. He directs the Summer Course in Affective Neuroscience and serves as Co-Editor-in-Chief of Personalized Medicine in Psychiatry. His leadership in the WFSBP anxiety disorder guidelines highlights his influence on clinical standards.

He directs multidisciplinary teams at the Personalized Medicine Center for Anxiety and Panic Disorders and Villa San Benedetto Menni's Department of Clinical Neurosciences. These units integrate psychiatric, neurological, and technological expertise to develop evidence-based protocols for anxiety disorders, emphasizing physiological monitoring and tailored interventions through collaborations with sleep clinics and respiratory specialists.