معرفی
Giacomo Maria Paganotti is an Adjunct Assistant Professor in the Department of Medicine, Division of Infectious Diseases at the Perelman School of Medicine, University of Pennsylvania. He is based in Botswana, where he leads the Botswana-UPenn Partnership molecular laboratory, collaborating with the University of Botswana and multiple international institutions including Duke, McMaster, Penn, and the University of Rome La Sapienza.
Research Interests: Dr. Paganotti's work spans malaria, HIV/AIDS, HPV, breast and cervical cancer, and pharmacogenetics. Initially trained as a malariologist, he has expanded his focus to investigate how human genetic variation influences drug response and disease progression in infectious and oncological contexts. His research emphasizes host-pathogen interactions, molecular epidemiology, and genetic determinants of treatment outcomes.
Publication Trends: His recent publications (2018–2021) reflect a strong focus on molecular and genetic aspects of disease in African populations, particularly in Botswana. Key themes include the spread of Plasmodium vivax in Duffy-negative individuals, CYP2B6 variants affecting antiretroviral therapy, epigenetic changes in cervical cancer with HIV co-infection, and vector genetics in malaria control. These works highlight interdisciplinary approaches combining genomics, epidemiology, and clinical medicine.
Scientific Recognition:
- No specific awards or fellowships are mentioned in the text.
Advising and Grants: While no formal students are listed, Dr. Paganotti mentors students and researchers through the Botswana-UPenn Partnership, involving students from the University of Botswana and international trainees. His sustained research output and leadership suggest active grant funding, though specific grants are not detailed.
Labs and Collaborations: He leads the molecular laboratory at the Botswana-UPenn Partnership, a hub for collaborative research involving multiple African and global institutions. His work integrates teams across disciplines including infectious diseases, oncology, and genetics.
