معرفی
George Thanassoulis, MD is a Professor in the Department of Medicine at McGill University's Faculty of Medicine and Health Sciences. He serves as a Senior Scientist at the Research Institute of the McGill University Health Centre (RI-MUHC) at the 5252 de Maisonneuve site, where he is affiliated with both the Cardiovascular Health Across the Lifespan Program and the Centre for Outcomes Research and Evaluation (CORE).
Dr. Thanassoulis specializes in cardiovascular genetics and prevention, with particular expertise in lipoprotein(a), aortic valve stenosis, and premature coronary artery disease. His research program focuses on identifying genetic determinants of cardiovascular disease, especially in the context of valvular heart disease. He leads an international consortium investigating genomic variation in aortic valve stenosis and has pioneered approaches to optimize cardiovascular prevention in young individuals.
Analysis of Dr. Thanassoulis' publication record reveals a strong emphasis on translational cardiovascular research, particularly at the intersection of genetics, lipidology, and clinical cardiology. His work spans basic science investigations into molecular mechanisms of aortic valve disease, large-scale genetic epidemiology studies using electronic health records, and clinical guideline development for cardiovascular prevention. A significant portion of his recent work focuses on lipoprotein(a) as both a genetic risk factor and therapeutic target.
Dr. Thanassoulis directs the MUHC Family Heart Clinic, which provides specialized care for patients with premature coronary artery disease and their families. Through this clinic, he implements precision medicine approaches to cardiovascular prevention based on genetic and family history risk factors. His leadership extends to national guideline committees, including the Canadian Cardiovascular Society, where he has contributed to developing evidence-based recommendations for dyslipidemia management.