معرفی
Gad Getz is a Core Institute Member at the Broad Institute of MIT and Harvard, where he directs the Cancer Genome Computational Analysis Group. He serves as Professor of Pathology at Harvard Medical School and Director of Bioinformatics in the Krantz Family Center for Cancer Research and Department of Pathology at Massachusetts General Hospital (MGH). Getz holds the prestigious Paul C. Zamecnik Chair in Oncology at MGH, signifying his leadership in cancer research.
His laboratory specializes in cancer genome analysis with two major components: characterization (cataloging genomic events during cancer evolution from normal cells through premalignancy to therapy resistance) and interpretation (analyzing these events across patient cohorts to identify cancer drivers and molecular subtypes). The lab develops computational tools that are part of robust analytical pipelines for national and international cancer genome projects.
- Current research focuses on cancer heterogeneity and clonal evolution across multiple cancer types
- Single-cell analysis of tumors and tumor microenvironment
- Drivers of resistance to cancer therapies
- Proteogenomic analysis of tumors
- Role of somatic mutations in normal tissues
Getz co-leads the primary TCGA Genome Data Analysis Center and the Broad's Proteogenomics Data Analysis Center, having contributed to projects analyzing over 10,000 cancer samples through initiatives like TCGA and PCAWG. He previously served on the NCI's Cancer Moonshot Blue Ribbon Panel and co-led one of three NCI Cloud Pilots.
His educational background includes a B.S. in physics and mathematics from Hebrew University, M.Sc. in physics from Tel-Aviv University, and Ph.D. in physics from the Weizmann Institute of Science. His postdoctoral training at the Broad Institute with Todd Golub focused on developing computational tools for miRNA expression analysis across cancers.
