GONG Xin

GONG Xin is an Associate Professor at the Department of Chemical Biology, School of Life Sciences, Southern University of Science and Technology (SUSTech), Shenzhen, China. His research focuses on structural biology, biochemical, and biophysical approaches to understand lipid metabolism regulatory proteins and their roles in disease mechanisms.

• Ph.D. in Biology (2015), Tsinghua University
• B.Eng. in Bioinformatics (2010), Huazhong University of Science and Technology
• Postdoctoral training at Princeton University (2017-2018) and Tsinghua University (2015-2017)

His work investigates the molecular architecture and functional dynamics of membrane proteins involved in lipid metabolism, including Hedgehog signaling, ceramide synthesis, and cholesterol trafficking. Techniques include cryo-electron microscopy, X-ray crystallography, and biochemical assays.

Recent publications highlight structural mechanisms of fungal drug resistance (2025), sphingolipid homeostasis regulation (2024), and insights into human lipid transporters like ABCA4 and ABCA3 (2021-2022). His studies often combine structural analysis with functional studies to reveal disease-related pathways.

• 2019 Outstanding Young Investigator Award, Guangdong Province
• 2019 National Leading Talent of Shenzhen
• 2019 Peacock Talent Plan (Level B), Shenzhen

Dr. Gong teaches advanced courses in Protein Engineering, Bioseparations, and Frontiers in Bioseparations. His lab at SUSTech leverages state-of-the-art cryo-EM facilities, including six 300kV Titan Krios microscopes, for high-resolution structural studies.