Frederic Chedin

Frédéric Chédin is a Professor in the Department of Molecular and Cellular Biology at the University of California Davis, College of Biological Sciences. He has held continuous faculty positions at UC Davis since 2004, progressing from Assistant Professor (2004-2010) to Associate Professor (2010-2015), and currently serving as full Professor (2015-present).

His research focuses on R-loop biology, DNA methylation, and epigenetic regulation. Chédin's laboratory investigates how RNA:DNA hybrids form, persist, and impact genome stability, with particular emphasis on their roles in transcription, chromatin organization, and disease mechanisms. His work has established foundational methodologies for R-loop detection and mapping, including critical assessments of common techniques like the S9.6 antibody.

Chédin's publication record demonstrates consistent leadership in R-loop research, with numerous high-impact papers in journals like PNAS, Nature Communications, and Molecular Cell. His recent work explores protein-mediated R-loop stabilization, R-loop classification systems, and connections between R-loops and topological stress management.

• Director of NIH T32 Predoctoral Training Program in MCB (2020-present)
• Co-Director of NIH T32 Program (2019-2020)
• Chair of Integrative Genetics and Genomics (2015-2019)

His laboratory trains numerous graduate students and postdoctoral researchers, with frequent collaborators including Stella Hartono and Lionel Sanz appearing as first authors on key publications. Chédin maintains active service roles in graduate education and program leadership at UC Davis.