معرفی
Frank LE FOLL serves as Professor and Deputy Director of SEBIO (Environmental Stress and BIOmonitoring of aquatic environments) at the University of Le Havre Normandy, France. His research focuses on bivalve immune defense systems, particularly hemocyte function in Mytilus edulis and related species, investigating cellular responses to pathogens, chemical contaminants, and environmental stressors.
His primary research interests include Marine Immunology, Bivalve Hemocyte Function, and Environmental Toxicology, with emphasis on inflammation mechanisms, phagocytic capacity, and oxidative burst responses. Using advanced cell biology techniques—including primary culture models, confocal imaging, flow cytometry, and time-lapse microscopy—his work addresses critical issues in aquatic pathobiology, vibrio infections, and mussel farm mortalities. Current projects examine immunotoxic impacts of anthropogenic pollutants and develop immunomarkers for water body biomonitoring.
Recent publications (2023-2025) reveal strong thematic continuity in marine immunotoxicology, with increasing focus on multi-stressor interactions (temperature, contaminants, pathogens) and field application of cellular biomarkers. Key trends include standardization of hemocyte motility as an inflammation marker, comparative studies across sentinel species (Mytilus, Dreissena, Palaemon), and development of integrated monitoring protocols for coastal and freshwater systems.
As Deputy Director of SEBIO, he oversees technical platforms including Cell Biology-Cytometry and Molecular Biology-Microbiology units. His laboratory operates at the University of Le Havre's main campus (Lebon site), utilizing specialized facilities for aquatic organism experimentation and environmental biomonitoring.
