Frank Jessen

Prof. Dr. Frank Jessen serves as a Professor and Cooperation Unit Leader at the German Center for Neurodegenerative Diseases (DZNE) in Cologne, affiliated with the University of Cologne. He coordinates the international DELCODE study and co-leads the clinical and neuropsychological assessment core of DZNE's clinical research section alongside Michael Wagner.

His research centers on early detection of Alzheimer's disease, with primary emphasis on clinical and neuropsychological assessment methodologies and magnetic resonance imaging (MRI). He spearheads global initiatives to define prodromal Alzheimer's symptoms like subjective cognitive decline (SCD), utilizing longitudinal cohort studies to develop novel biomarkers and improve disease trajectory prediction. His work bridges clinical practice with neuroimaging to establish diagnostic criteria for pre-dementia stages.

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Dr. Jessen directs the DELCODE study, which tracks high-risk patients from memory clinics across multiple sites, and maintains leadership in DZNE's clinical research infrastructure through his neuropsychological assessment core.