معرفی
Francesco Simone Ruggeri is an Associate Professor at Wageningen University & Research (WUR), Netherlands, leading research in Physical Chemistry and Soft Matter. He holds a PhD in Biophysics from École Polytechnique Fédérale de Lausanne (EPFL, Switzerland) and completed a Junior Research Fellowship at the University of Cambridge (UK). His work focuses on nanoscale characterization of biomolecular systems using advanced microscopy and spectroscopy techniques.
Education:
- PhD in Biophysics, EPFL (2015)
- MSc in Physics, University of Catania (2010)
- BSc in Physics, University of Catania (2007)
Research Interests:
- Single-molecule AFM-based approaches for studying biomolecular processes
- Development of infrared nanospectroscopy for biological samples
- Structural analysis of amyloid proteins in neurodegenerative diseases (Alzheimer’s, Parkinson’s)
- Phase separation and liquid-liquid condensates in cells
- Nanochemical biomarkers for disease detection
Key Contributions:
- Pioneered AFM-IR for single-molecule chemical fingerprinting in liquid environments
- Discovered early-stage phase separation in protein aggregation
- Identified structural polymorphism in amyloid fibrils
- Developed microfluidic platforms for biomaterial analysis
Grants & Projects:
- Leading the NanoNu Marker project for early dementia detection
- Investigating biomarkers for cognitive aging (NWO-funded)
- Developing functional surfaces and nanoscale tribology
Labs & Teams: Manages the Microscopy and Nanospectroscopy of Biomolecular Systems lab at WUR, collaborating with interdisciplinary teams in physics, chemistry, and neuroscience.
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