معرفی
Francesca Luca is an Assistant Professor at Wayne State University, jointly appointed in the Center for Molecular Medicine and Genetics and the Department of Obstetrics and Gynecology. Her research integrates evolutionary and functional genomics to explore genetic and molecular mechanisms underlying inter-individual and inter-population differences in complex traits.
- University: Wayne State University
- Academic Rank: Assistant Professor
- Email: fluca@wayne.edu
Research Interests: Dr. Luca investigates how phenotypic differences evolved as humans adapted to changing environments, focusing on gene-environment interactions, nuclear receptor pathways (e.g., estrogen receptors), and health disparities. Her work employs functional genomics techniques like ChIP-seq and RNA-seq on diverse human populations.
Publications: Recent studies include analyses of gene-environment interactions in SARS-CoV-2 responses (2023), single-cell placental transcription in preterm birth (2019), and evolutionary adaptations to dietary shifts (2010). She also explores host-microbiome interactions (2018) and genetic variations in NAT2 and SGK1 genes.
Collaborative Work: Dr. Luca's lab collaborates on projects spanning pharmacogenomics, maternal-fetal medicine, and systems-level genetic characterization of health disparities. Her methodologies bridge evolutionary theory with clinical applications in obstetrics and gynecology.
