Jeyasuria Pancharatnam

Jeyasuria Pancharatnam is an Assistant Professor at Wayne State University School of Medicine, jointly appointed in the Department of Obstetrics and Gynecology and the Department of Physiology. His research integrates molecular biology and transgenic approaches to explore reproductive endocrinology and physiology, with a focus on nuclear receptor functions and mechanisms controlling labor timing.

• Established expertise in steroidogenic factor-1 (SF-1) and estrogen receptor isoforms.
• Developed Cre-Lox strategies for maternal-fetal signaling in imprinting and preterm birth.

Research Themes:

• Characterization of ERα splice variants in uterine quiescence during pregnancy.
• Investigation of splicing mechanisms that alter gene functionality in myometrial cells.
• Deciphering maternal-fetal gene interactions in intrauterine growth restriction and preeclampsia.
• Historical work on sex determination in reptiles via P450 aromatase expression.

Article Trends: Recent publications highlight ERδ7 as a therapeutic target for preterm birth, LZTFL1 in male fertility, and endoplasmic reticulum stress in uterine physiology. His work bridges molecular endocrinology, transgenic models, and pregnancy complications.

Academic Contributions: Teaches graduate and medical courses on reproductive biology, stem cell biology, and testis development. Serves as a mentor in the Wayne State UROP program and collaborates with the Perinatology Research Branch/NIH/NICHD.