معرفی
Felix Winter is a researcher at the Department of Systems Biology and Bioinformatics (SBI) within the Faculty of Computer Science and Electrical Engineering at the University of Rostock. He has been working as a Researcher at ASD GmbH in the VPH Dare@IT project since 2013 and has been a PhD Student in Systems Biology at the University of Rostock since 2009, funded by the Faculty of Interdisciplinary Research, Department Aging Sciences and Humanities.
His educational background includes a Diplom in Business Mathematics (comparable to a master's degree) from the University of Rostock, completed between 2001 and 2009.
Winter's research focuses on understanding the pathophysiology of Alzheimer's disease through mathematical modeling approaches. His specific interests include:
- In-vivo regulation of Amyloid-β (Aβ) abundance
- Energy metabolism and brain imaging in Alzheimer's disease
- Protein aggregation mechanisms in neurodegenerative diseases
- Mathematical modeling of brain energy metabolism and its alterations in Alzheimer's disease
- Transport mechanisms of Aβ across the blood-brain barrier
- Mathematical analysis of diagnostic signals used in Alzheimer's patients
His publication record demonstrates expertise in applying systems biology to understand Alzheimer's disease mechanisms. His work spans from developing computational models of Aβ aggregation to analyzing brain metabolism's influence on clinical diagnostic measures. Using mathematical models of brain energy metabolism, Winter revealed Alzheimer's-specific alterations in clinical diagnostic measures. His research connects computational approaches with experimental neuroscience to understand the relationship between disease mechanisms and the aging process.
Winter has established collaborations with prominent researchers including Olaf Wolkenhauer (his primary academic mentor) and Jens Pahnke from the Neurodegeneration Research Laboratory in the Department of Neurology at the University of Rostock. His participation in the VPH Dare@IT project indicates involvement in research initiatives focused on virtual physiological human modeling. His work contributes to both fundamental aging research and potential therapeutic approaches for Alzheimer's disease.
