معرفی
Felix Yarovinsky is a Professor in the Department of Microbiology and Immunology and the Center for Vaccine Biology and Immunology at the University of Rochester School of Medicine and Dentistry. His laboratory is actively engaged in research on innate immunity to protozoan parasites and the role of Paneth cells in intestinal homeostasis and inflammation.
Dr. Yarovinsky obtained his M.D. from Russian State Medical University followed by postdoctoral training at the US National Institutes of Health. His research focuses on innate host responses to parasitic infections and immunoregulatory mechanisms controlling inflammation in the gastrointestinal tract. His laboratory aims to understand the cellular and molecular mechanisms of host resistance to protozoan parasites, particularly how innate immune cells cooperate in regulating IFN-gamma responses to infection.
His recent publications demonstrate a strong focus on Toxoplasma gondii infection mechanisms, with particular emphasis on IFN-γ signaling pathways, Paneth cell biology, and the interplay between intestinal microbiota and host immune responses. His work spans from basic cellular and molecular studies to translational applications in understanding host-pathogen interactions.
Dr. Yarovinsky leads an active research laboratory with multiple postdoctoral scholars, research staff, and graduate students working on projects related to mucosal immunity to Toxoplasma gondii, Paneth cell functions in intestinal homeostasis, and neutrophil roles in host defense and inflammation.
His laboratory utilizes a multidisciplinary approach including germ-free mouse models, cellular and molecular techniques, and structural analyses to investigate mucosal immune cells and their contribution to microbiota composition and intestinal immune responses.
