Farhad Kosari

Farhad Kosari, Ph.D., is an Associate Professor in the Department of Molecular Medicine at Mayo Clinic, Rochester, Minnesota. He also holds the academic rank of Assistant Professor of Biochemistry and Molecular Biology. His research is centered on molecular oncology, with a strong emphasis on genomics, cancer biomarkers, and translational diagnostics in prostate cancer, lung adenocarcinoma, and mesothelioma.

Dr. Kosari earned his Ph.D. in Biochemistry and Molecular Biophysics from the University of Pennsylvania, complemented by advanced degrees in Electrical Engineering (M.S. from Virginia Tech, B.S. from Texas Tech University), reflecting his interdisciplinary approach to biomedical research.

His research interests span genomic alterations in cancer, chromosomal rearrangements, cell-free DNA analysis, immunotherapy response biomarkers, and early detection assays. He leverages deep sequencing, nanopore technology, and bioinformatics to uncover molecular drivers of malignancy and to develop non-invasive diagnostic tools.

The trends in his recent publications (2018–2025) highlight a focus on targeted cancer therapies, PROTAC-based degradation, immune monitoring in mesothelioma, and molecular diagnostics in non-neoplastic tissues. His work integrates genomics, transcriptomics, and clinical data to advance precision oncology.

Scientific Awards and Recognition:

• No specific awards are listed in the provided text.

Dr. Kosari has been actively involved in grant-funded research, serving as Principal Investigator on projects funded by the Congressionally Directed Medical Research Programs and as Co-PI on a National Cancer Institute grant. His work supports postdoctoral fellowships and collaborative training programs. He is embedded in key research centers including the Mayo Clinic Comprehensive Cancer Center, the Epidemiology and Genetics of Lung Cancer Research Program, and the David F. and Margaret T. Grohne Cancer Immunology and Immunotherapeutics Program. His laboratory collaborates extensively with clinicians and scientists in oncology, pathology, and immunology to translate molecular findings into clinical applications.