جستجوی استاد راهنمای دانشگاهی

Prof. Ralph Hückelhoven is a Professor of Phytopathology at the Technical University of Munich (TUM), affiliated with the TUM School of Life Sciences. His research focuses on the molecular and biological mechanisms underlying plant diseases, particularly plant immunity, pathogen exploitation of signal transduction, and host-pathogen interactions. He leads the Chair of Phytopathology at TUM since 2006, following academic roles at universities of Kiel and Hohenheim. Education: PhD (1999) and habilitation in molecular phytopathology (2005) from Justus Liebig University Giessen, after a biology degree at RWTH Aachen University. Awards: Julius Kühn Prize (2004) and leadership of a DFG Junior Research Group (2002-2006). His research spans plant immunity at cellular and molecular levels, including studies on receptor kinases (e.g., MIK2, LORE), RAC GTPases (e.g., RACB), and metabolomics-driven insights into pathogen resistance. He has published over 100 peer-reviewed articles, examining topics like fungal toxins, volatile signaling, and crop disease management. Key publications include work on Arabidopsis immune receptors, barley powdery mildew susceptibility factors, and Fusarium head blight resistance. Research integrates genetics, proteomics, and metabolomics to advance disease-resistant crop development. His lab investigates host-pathogen interactions across scales—from molecular signaling to field epidemiology—contributing to sustainable agricultural strategies against plant pathogens.

• Plant Pathology
• Molecular Biology
• Plant Immunity
• +۳ مورد دیگر

Cheryl Walker, Ph.D., is a Professor in the Departments of Molecular and Cellular Biology, Medicine, and Molecular and Human Genetics at Baylor College of Medicine. She serves as Director of the Center for Precision Environmental Health and Co-Leader of the Chromatin Biology Program at the Dan L Duncan Comprehensive Cancer Center. Her research focuses on gene-environment interactions, epigenomics, and the molecular mechanisms underlying diseases such as cancer, fibroids, and non-alcoholic fatty liver disease (NAFLD). Key areas include the role of chromatin remodelers like SETD2 in genomic stability and their dual functions in cytoskeletal dynamics. She has pioneered studies on how early-life environmental exposures, such as endocrine-disrupting chemicals (EDCs), reprogram the epigenome to increase disease susceptibility later in life. Dr. Walker’s work is funded by NIH and DOD grants, including leadership of the TaRGET II Consortium for environmental epigenomics. Her lab employs cutting-edge technologies like ChIP-seq and RNA-seq to study epigenetic reprogramming. Notable contributions include discoveries linking SETD2 methylation to microtubule stability and genomic integrity, and identifying epigenetic signatures of environmental exposures in health disparities research. Education: Ph.D. in Molecular Biology Affiliations: Baylor College of Medicine, Gulf Coast Center for Precision Environmental Health Her awards include election to the National Academy of Medicine and fellowships in the American Association for the Advancement of Science (AAAS) and American Thoracic Society (ATS). The lab actively collaborates on translational projects, including biomarker development and disaster-related health studies following events like Hurricane Harvey. Key Research Themes: Epigenetic drivers of cancer and fibrosis Environmental epigenomics and disease risk Chromatin-cytoskeleton cross-talk in disease

• Epigenomics
• Cancer Biology
• Molecular Genetics
• +۳ مورد دیگر

Ben Raphael is a Professor in the Department of Computer Science at Princeton University, with affiliations at the Lewis-Sigler Institute for Integrative Genomics, Omenn-Darling Bioengineering Institute, and Center for Statistics and Machine Learning. He is also an Affiliate Faculty member at the Rutgers Cancer Institute of New Jersey, Irving Institute for Cancer Dynamics at Columbia University, and New York Genome Center. His research focuses on computational methods for analyzing large-scale biological data, emphasizing cancer evolution, network/pathway analysis, and structural variation in genomes. Research Trends: His recent work spans cancer lineage trees, spatial transcriptomics, optimal transport for developmental models, and network analysis of mutations. Articles highlight applications in prostate cancer, pancreatic cancer, and single-cell genomics. Scientific Awards: 2024 ACM Fellow 2023 RECOMB Test of Time Award 2022 RECOMB Test of Time Runner-Up 2021 ISCB Innovator Award 2021 RECOMB Best Paper Runner-Up 2020 ISCB Fellow 2020 AACR Team Science Award 2011 NSF CAREER Award 2013 RECOMB Best Paper 2010-2012 Sloan Research Fellowship Advising: He has mentored numerous Ph.D. students and postdoctoral fellows, many of whom have transitioned to academic and industry roles. Current advisees include Uthsav Chitra, Gillian Chu, and Alexander Strzalkowski. Labs & Teams: Raphael leads the Raphael Lab at Princeton, developing tools like HotNet2, CHISEL, and HATCHet for cancer genomics and network analysis.

• Bioinformatics
• Computational Biology
• Cancer Genomics
• +۶ مورد دیگر

G. Petur Nielsen, MD is a Professor of Pathology at Harvard Medical School and serves as Subspecialty Head, Bone and Soft Tissue Pathology at Massachusetts General Hospital . With a clinical focus on bone and soft tissue tumors, his expertise spans diagnostic pathology, molecular genetics of neoplasms, and ancillary testing applications. Research interests center on Pathology and biology of bone/soft tissue tumors Molecular genetics of bone and soft tissue neoplasms Chordoma and sarcoma research Epithelioid vascular tumor differentiation Mesenchymal tumors of the female genital tract His work includes landmark studies on tumor misdiagnosis rates, immunohistochemical profiling, and genomic analysis of chordomas. Scientific contributions appear in leading journals like Nature and American Journal of Surgical Pathology , with major emphasis on Molecular tumor classification Mutational signature analysis Translational oncology Diagnostic accuracy improvement Genomic instability mechanisms

• Bone and Soft Tissue Pathology
• Molecular Genetics of Bone Tumors
• Chordoma Research
• +۵ مورد دیگر

Jochen Wolf is Chair of the Evolutionary Biology Division at Ludwig-Maximilians-Universität München (LMU) and a Max Planck Fellow of the Max Planck Institute for Biological Intelligence since 2022. His research integrates evolutionary biology, genomics, and ecology to address fundamental questions about speciation, adaptation, and biodiversity across multiple biological systems. Dr. Wolf's research program applies an integrative approach to understand microevolutionary processes and genetic mechanisms underlying species divergence. His work combines large-scale genomic analyses with laboratory and field experiments to characterize genomic divergence across populations and species. Key empirical systems include natural populations of birds (particularly corvids, swallows, and cuckoos), marine mammals (pinnipeds and killer whales), plant communities, and experimental evolution in fission yeast. His research spans multiple scales from immediate microevolutionary processes to broader evolutionary patterns across time. His recent publications reveal a sophisticated integration of genomic, epigenetic, and ecological perspectives. A notable trend shows increasing focus on structural genomic variation, chromosomal rearrangements, and epigenetic mechanisms as drivers of evolutionary processes. His work demonstrates how these molecular mechanisms interact with ecological factors to shape patterns of biodiversity and adaptation. Dr. Wolf's research has gained significant recognition through publications in top-tier journals including Nature, Science, and Nature Ecology & Evolution. His groundbreaking studies on crow hybrid zones, killer whale ecotypes, and experimental evolution of speciation have been featured in prominent media outlets such as The New Yorker, The Guardian, Scientific American, and Der Spiegel, demonstrating the broad impact of his work. As Principal Investigator, Dr. Wolf actively mentors doctoral students and postdoctoral researchers, fostering the next generation of evolutionary biologists. His lab maintains strong international collaborations, particularly through affiliations with SciLifeLab in Uppsala. Research in his group is supported by multiple funding sources including German Research Foundation grants and European Union programs, enabling both fundamental research and applications to conservation biology. The Wolf lab operates within LMU's Division of Evolutionary Biology, which provides access to state-of-the-art facilities including the Leibniz Supercomputing Centre. The lab maintains strong connections with the Max Planck Institute for Biological Intelligence and SciLifeLab in Uppsala, creating a rich collaborative environment for interdisciplinary research in evolutionary genomics. This network enables comprehensive studies spanning from molecular mechanisms to ecological and evolutionary consequences across diverse biological systems.

• Evolutionary Biology
• Speciation Genomics
• Genome Evolution
• +۷ مورد دیگر

Haynes Heaton is an Assistant Professor in the Department of Computer Science and Software Engineering at Auburn University. He holds a Ph.D. in Computational Biology from Cambridge University, an M.D. from Brown University, and a B.S. in Computer Science from Brown University. His interdisciplinary work bridges computational methods with biomedical applications, focusing on genomic technologies for malaria research and single-cell analysis. Research interests include genome sequencing of malaria vectors (e.g., Anopheles mosquitoes), development of bioinformatics tools (e.g., LCSKPOA, Souporcell), and structural variation analysis in human and pathogen genomes. His work has contributed to chromosomal reference genomes for multiple malaria mosquitoes, advancing understanding of vector biology and disease transmission. Publications highlight innovations in genome assembly, single-cell RNA-seq deconvolution, and computational methods for genomic data analysis. While no explicit awards are listed, his research has been featured in Auburn Engineering news for breakthroughs in leukemia diagnostics via software development. He collaborates with medical and computational teams to translate genomic insights into clinical applications. No advising records or grants are explicitly detailed in the provided text.

• Computational Biology
• Genomics
• Bioinformatics
• +۴ مورد دیگر

Rachel O'Neill serves as a Board of Trustees Distinguished Professor in the Department of Molecular and Cell Biology at the University of Connecticut's College of Liberal Arts and Sciences. Her research bridges molecular genetics, cytogenetics, and computational genomics to investigate fundamental mechanisms of genome stability and evolution across diverse eukaryotic species. Her primary research interests focus on retroelement transcription, centromere function, chromosome evolution, and species-specific genomic adaptations. O'Neill's lab pioneers telomere-to-telomere (T2T) genome assembly methodologies using next-generation sequencing technologies, establishing non-traditional model organisms including marsupials, monotremes, birds, marine species, plants, and insects for comparative genome biology studies. Human Telomere-to-Telomere Consortium Primate T2T Consortium Gibbon T2T Consortium Earth Biogenomes Project Ruminant T2T Consortium Fly T2T Consortium Deep Ocean Genomes Project Antarctic Genomes Consortium Colossal Foundation UConn’s Biodiversity and Conservation Genomics program O'Neill's recent publications (2021-2025) demonstrate leadership in large-scale genomics initiatives, with significant contributions to understanding centromere biology, sex chromosome evolution, and conservation genomics. Her work spans marsupial mole genomics, ruminant chromosome evolution, and epigenetic regulation of X-chromosome inactivation, reflecting her lab's broad impact across evolutionary biology, conservation, and fundamental genome science. Her laboratory actively trains students through cohort-based programs including the RaMP Cohort and Biodiversity and Conservation Genomics Program, securing substantial collaborative funding through multi-institutional consortia. The lab maintains strong infrastructure for advanced genome assembly and epigenomic analysis, with particular expertise in challenging repetitive regions and non-model organism genomics.

• Genome Stability
• Retroelement Transcription
• Centromere Function
• +۵ مورد دیگر

David Weisblat is a Professor in the Department of Molecular and Cell Biology at UC Berkeley's College of Letters & Science. His research focuses on developmental and evolutionary processes in glossiphoniid leeches (e.g., Helobdella ), particularly their segmentation mechanisms and molecular phylogeny within Lophotrochozoa. He leads studies integrating embryological, genomic, and genetic approaches to understand how developmental pathways evolved across bilaterian animals. Research Interests: Weisblat’s work addresses how cell fates and signaling pathways (WNT, NOTCH, TGFβ) shape leech development, with emphasis on the evolutionary origins of segmentation. His lab combines microinjection techniques, transcriptome analysis, and CRISPR mutagenesis to explore stem cell dynamics and conserved developmental programs. Key Projects: Current efforts investigate grandparental stem cell divisions in segmentation and intercellular signaling during early embryogenesis. The lab’s genomic resources—including BAC libraries and EST databases—facilitate comparative studies across Lophotrochozoan taxa. Lab Contributions: The Weisblat lab pioneered Helobdella as a model organism, enabling breakthroughs in Evo-Devo. Their findings bridge developmental plasticity and evolutionary innovation, particularly in annelids versus arthropods/deuterostomes.

• Developmental Biology
• Evolutionary Developmental Biology (Evo-Devo)
• Molecular Phylogenetics
• +۴ مورد دیگر

Alex Mogilner is a Professor of Mathematics and Biology at New York University's Courant Institute and Department of Biology. His research focuses on computational and mathematical modeling of cellular processes, including cell motility, mitosis, actin dynamics, and galvanotaxis. He collaborates closely with experimentalists to bridge theoretical and empirical cell biology. Education: Ph.D., Applied Mathematics, University of British Columbia, Canada (1995) Ph.D., Physics, USSR Academy of Sciences (1990) M.Eng., Engineering Physics, Ural Polytechnic Institute, USSR (1985) Research Interests: Mathematical modeling of molecular machines in cells Mitotic spindle dynamics and chromosome segregation Actin-myosin contraction mechanisms Galvanotaxis and electrotaxis in cell migration Cellular biophysics and mechanochemical processes Selected Publications Highlights: Developed models for mitotic spindle assembly and error correction Investigated mechanisms of cell polarization and turning Studied actin network contraction and cytoskeletal dynamics Explored galvanotactic cell migration in electric fields Labs/Teams: Leads a computational modeling lab at NYU, collaborating with experimental groups globally in cell biology, biophysics, and systems biology.

• Computational Biology
• Cell Biophysics
• Mathematical Biology
• +۵ مورد دیگر

Professor Ian Henderson is a leading academic in the Department of Plant Sciences at the University of Cambridge, affiliated with the School of Biological Sciences. He holds the title of Professor of Genetics and Epigenetics and has been a Royal Society University Research Fellow and Gatsby Resident Fellow since 2008. Education: BA in Biological Sciences (University of Oxford, 1997-2000); PhD in Plant Genetics (John Innes Centre, 2000-2004) under Prof. Caroline Dean His research focuses on genetic and epigenetic control of meiotic recombination in plant genomes, with an emphasis on crossover frequency, chromatin interactions, and centromere evolution. His group uses model organisms like Arabidopsis thaliana , wheat, potato, and oak trees. Key trends in his recent publications include centromere genomics , epigenetic regulation of recombination , and application of long-read sequencing to resolve complex genomic regions. Collaborations with agro-biotech companies (Bayer Biosciences, Solynta) aim to translate findings into crop breeding technologies. Scientific Awards EMBO Member (2022) Society for Experimental Biology President's Medal (2013) Royal Society University Research Fellow (2008-2016) Gatsby Research Fellow (2008-2016) EMBO Long Term Fellowship (2004-2008) Professor Henderson's work bridges fundamental research on plant genome evolution with applied strategies to control recombination for climate-resilient crops. His lab employs advanced techniques including nanopore sequencing , ChIP , and high-performance computing for genome analysis.

• Genetics
• Epigenetics
• Meiosis
• +۴ مورد دیگر

Shweta U. Dhar, MD, MS, FACMG, FACP, is a Professor and Medical Director of Adult Genetics at Baylor College of Medicine (BCM) in Houston, TX. She serves as Section Chief of Genetics at the Michael E. DeBakey VA Medical Center and is a member of the Dan L Duncan Comprehensive Cancer Center. She holds certifications from the American Board of Internal Medicine and American Board of Medical Genetics. Education includes: MBBS from NHL Municipal Medical College, Ahmedabad, India (1997) Residency in Pathology & Microbiology at Gujarat Cancer Research Institute (1999) MS in Biotechnology from Stephen F Austin State University, TX (2001) Internal Medicine Residency at New York INF Beekman Downtown Hospital (2006) Medical Genetics Fellowship at Baylor College of Medicine (2008) Her research focuses on diagnosis and management of adult genetic conditions, including: Single-gene disorders, chromosomal abnormalities, and familial cancer syndromes Cancer risk assessment and reproductive genetics Medical education innovation in genetics/genomics Healthcare delivery models for complex genetic conditions She directs BCM's Genetics course and founded the Genetics & Genomics Pathway for medical students. Recent publications demonstrate strong focus on clinical applications of genetics in neurodevelopmental disorders (Alexander disease, autism), cancer risk management (BRCA1, retinoblastoma), and healthcare system improvements. Her work frequently spans neurogenetics, cancer genetics, and medical education. Awards and honors: Fulbright & Jaworski Teaching & Evaluation Award (2013) Rising Star Clinician Award (2014) Fulbright & Jaworski Educational Leadership Award Clark Faculty Service Award (2018) Women of Excellence Award (2020) As Chair of the ACMG Adult Genetics Special Interest Group, she launched the Adult & Cancer Diagnostic Dilemmas session at national meetings. She serves on the ACMG Board of Directors as Clinical Director and leads clinical operations across BCM, VA, and Harris Health System genetics clinics.

• Adult Genetics
• Cancer Genetics
• Genetic Disorders
• +۲ مورد دیگر

Camille Berthelot is a Principal Investigator and head of the Comparative Functional Genomics research group at the Institut Pasteur in Paris, France. Her work lies at the intersection of evolutionary biology, genomics, and reproductive physiology, with a focus on understanding how genomic changes drive evolutionary innovations in vertebrates, particularly the evolution of menstruation in primates. Her research leverages cutting-edge technologies including single-cell RNA sequencing, organoid models, and computational frameworks to compare gene expression and regulation across species such as humans, macaques, and mice. She investigates how evolutionary changes in gene function contribute to novel traits and how these relate to diseases like endometriosis. A major focus is the use of menstrual fluid as a non-invasive biomarker source for endometriosis, a direction highlighted in her systematic review published in Reproductive Biology and Endocrinology . Her recent publications span high-impact journals such as Science , Genome Research , and Nature Ecology & Evolution , covering topics from teleost fish phylogeny to regulatory evolution in mole-rats. These works reveal a consistent trend in using comparative genomics to decode deep evolutionary questions, often in collaboration with institutions like QMUL and INSERM. ERC Starting Grant (EVOMENS) – Decoding the genetics of menstruation evolution in primates Collaborative project on hypoxia adaptation in mole-rats Development of bioinformatics tools like FINSURF for non-coding variant classification She actively mentors a team of postdocs, PhD students, and master’s interns, including Claire Lavergne, Leo Zeitler, and Eulalie Liorzou. Former members such as Malgorzata Gazda and Axelle Brulport have gone on to independent academic positions, reflecting her role in training next-generation scientists. Camille Berthelot returned from maternity leave in June 2024 and remains actively engaged in research, publication, and team leadership at the Institut Pasteur.

• Comparative Functional Genomics
• Evolutionary Genomics
• Gene Regulation
• +۱۲ مورد دیگر

Janine Deakin is Professor and Executive Dean of the Faculty of Science and Technology at the University of Canberra. She holds a PhD from Macquarie University (1998) and completed postdoctoral research at the University of Texas Health Science Center and Australian National University. Her research focuses on comparative genomics, chromosome evolution, and conservation genetics in marsupials and reptiles. Education: PhD in Immunological relationship of mother-pouch young relationships in the brushtail possum, Macquarie University (1998) Her research explores chromosomal speciation, sex determination mechanisms, and transmissible cancers like devil facial tumour disease, with strong emphasis on conservation applications. She employs cutting-edge genomic technologies to understand evolutionary adaptations in Australian wildlife. Recent publications demonstrate a consistent focus on chromosome dynamics across species, utilizing Hi-C mapping, telomere analysis, and comparative genomics to investigate genome reorganization in reptiles, marsupials and mammals. Her work frequently bridges molecular biology with conservation priorities. Scientific Awards: ARC Future Fellowship (2010) She has supervised numerous PhD students and leads collaborative initiatives including the Oz Mammals Genomics consortium. Her laboratory investigates chromosomal rearrangements impacting gene flow in threatened species.

• Genomics
• Chromosome Evolution
• Marsupial Genetics
• +۲ مورد دیگر

Dr. Stephanie Panier serves as a Max Planck Research Group Leader at the Max Planck Institute for Biology of Ageing in Cologne, Germany, and as a Principal Investigator at the Institute for Genome Stability in Aging and Disease within the Medical Faculty of the University of Cologne. Her research program investigates the fundamental mechanisms by which cells maintain genome stability through sophisticated DNA damage response pathways. Her academic journey includes: PhD in Molecular Genetics from the University of Toronto (2008-2013) under Prof. Daniel Durocher Postdoctoral training at the Francis Crick Institute in London (2013-2019) with Prof. Simon Boulton Undergraduate studies in Biology at Ruprecht-Karls-Universität Heidelberg, Germany (2001-2006) Dr. Panier's laboratory focuses on two central questions in genome stability research: how DNA damage response pathways interact with telomere maintenance mechanisms, and how RNAs and RNA-binding proteins organize chromatin-based responses to DNA lesions. Her team employs cutting-edge cell biological and omics approaches to identify and characterize RNA-binding proteins at DNA damage sites, mapping their chromatin dynamics and interactions following genotoxic stress. This research has significant implications for understanding aging-associated diseases driven by genomic instability, including cancer and neurodegeneration. Analysis of her publication record reveals consistent contributions to understanding DNA repair mechanisms, with recent work expanding into cancer biology, telomere maintenance in alternative lengthening pathways, and the emerging role of RNA metabolism in genome stability. Her scientific achievements have been recognized through: Vivash Award for best PhD thesis (2013) FEBS Excellence Award (2023) EMBO Long-Term Fellowship (2013-2014) Vanier Canada Graduate Scholarship (2010-2013) Boehringer Ingelheim Fonds PhD Fellowship (2008-2010) EIRR21st Fellowship (2023) Dr. Panier actively contributes to the scientific community through leadership roles including Vice Coordinator of the DFG Research Unit FOR5504 (2023-2026), membership on the advisory board of the German Society for Research on DNA Repair since 2022, and representation on the Biology and Medicine Section of the Max Planck Society's scientific council since 2022. She also serves as a Principal Investigator in the Cologne Excellence Cluster 'Cellular Stress Responses in Aging-Associated Diseases' (CECAD). Her laboratory comprises postdoctoral researchers and PhD students working collaboratively to advance our understanding of genome stability mechanisms in aging, with current projects focusing on RNA-binding proteins in DNA damage response and telomere maintenance pathways.

• Genome Stability
• DNA Damage Response
• Aging Research
• +۴ مورد دیگر

Dr. Robin Kochel is an Associate Professor at the Baylor College of Medicine , Department of Pediatrics. She leads the Kochel Lab for Clinical Autism Research , focusing on autism spectrum disorder (ASD), developmental regression, genotype-phenotype relationships, and vaccine hesitancy. Her work bridges clinical research and community engagement through collaborations with Texas Children's Hospital and SPARK for Autism. NIH Grants : R03HD080998 (Paternal Brain Responses to Infant Cues) and R03HD072102 (Carnitine Deficiency and ASD Regression) Dr. Kochel investigates parental perceptions of autism etiology, particularly vaccine-related concerns, and their impact on healthcare decisions. Her research spans genetic testing in ASD, teletherapy for anxiety management, and diversity in research recruitment . She also explores 16p11.2 chromosomal rearrangements and their links to language, cognition, and neuropsychiatric outcomes. Recent publications highlight her focus on CBT interventions for autistic youth, genetic subtypes , and cross-cultural vaccine hesitancy . Collaborators include institutions like the Simons VIP Consortium and We Rock the Spectrum . Dr. Kochel prioritizes translating findings into community resources for families and advocates for evidence-based recruitment in autism studies.

• Autism Spectrum Disorder
• Developmental Delays
• Genotype-Phenotype Relationships
• +۷ مورد دیگر