Fan Liu

Fan Liu is a Research Assistant Professor in the Department of Biochemistry and Molecular Biology at Sylvester Comprehensive Cancer Center, focusing on epigenetic mechanisms in hematopoiesis and cancer. They hold a primary appointment at the Cancer Center and investigate how epigenetic dysregulation drives malignancies like myeloid neoplasms and myelodysplastic syndrome.

• Research Themes: Epigenetic regulation, transcriptional dynamics, innate immunity in cancer, JAK2 signaling, PRMT5/PRC2 interactions, and blood cell development.
• Key Collaborations: Affiliated with Sylvester Comprehensive Cancer Center for translational cancer research.

Recent publications analyze CARM1 enzymatic activity, Trim33's role in dendritic cell differentiation, and PRMT5's antagonism of PRC2-mediated repression, highlighting their work at the interface of epigenetics and immune signaling in oncology. Their studies span molecular mechanisms in hematopoietic malignancies and innovative approaches to chemotherapy resistance in melanoma.