Ethan Weiss

Ethan Weiss, MD, is an Associate Professor in Residence in the Department of Medicine at the University of California, San Francisco (UCSF), School of Medicine. He is a board-certified cardiologist with clinical expertise in general and preventive cardiology, focusing on genetics of coronary disease, risk assessment, and heart disease in young patients.

Dr. Weiss earned his MD from Johns Hopkins University in 1996 and completed his cardiology fellowship at UCSF. His research integrates genetic models to investigate metabolic disorders such as obesity, fatty liver disease, and diabetes, as well as the coagulation system, aiming to develop safer antithrombotic therapies.

His research interests include:

• Metabolic regulation and insulin resistance
• Genetic basis of lipid disorders
• Time-restricted eating and ketogenic diets
• JAK2 and growth hormone signaling in metabolism
• Sex differences in thrombosis and liver disease
• Digital health interventions for weight management

Dr. Weiss has published extensively in top-tier journals including The Lancet, Science, JAMA Internal Medicine, and Diabetes. His recent work centers on lipid-lowering therapies, body composition analysis via 3D scanning, and clinical trials on dietary patterns such as time-restricted eating. His publications demonstrate a strong trend toward translational research bridging molecular mechanisms with clinical applications in cardiometabolic health.

He collaborates with key investigators at UCSF, including Eric Vittinghoff and Jeffrey Olgin, and has contributed to significant studies on metabolic liver disease, clotting disorders, and nutritional interventions. While no formal awards are listed in the provided text, his work has been widely cited and featured in media outlets and social platforms.

Dr. Weiss is actively involved in clinical trials and digital health research, particularly in evaluating mobile apps for dietary adherence and metabolic outcomes. He maintains a public presence on X (@ethanjweiss) and has participated in public discussions on metabolism, gene editing, and physician entrepreneurship.

He is affiliated with the UCSF Cardiology division and contributes to both patient care and biomedical research, embodying a physician-scientist role dedicated to advancing understanding and treatment of metabolic and cardiovascular diseases.