معرفی
Aycha Bleeker is a researcher specializing in metabolic disorders, with a focus on glycogen storage disease type Ia and hepatic metabolism. Her work spans biochemistry, molecular biology, and nutrition science, leveraging mouse models to investigate disease mechanisms and therapeutic interventions.
Key research themes include:
- Role of ChREBP signaling in glucose and lipid homeostasis
- Impact of dietary patterns on healthy aging and metabolic health
- Metabolic consequences of mitochondrial fatty-acid oxidation disorders
- Regulation of endogenous glucose production in human clinical studies
Recent collaborative work has explored:
- Liver disease progression in glycogen storage disorders
- Interplay between hypoglycemia and hypertriglyceridemia
- Effects of dietary restriction on aging metabolism
Her interdisciplinary approach integrates genetic research, nutritional science, and metabolic modeling, supported by data sharing through repositories like figshare and DataverseNL.
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