معرفی
Eric S. Witze is an Associate Professor of Cancer Biology at the Perelman School of Medicine, University of Pennsylvania, and an Assistant Investigator at the Abramson Family Cancer Research Institute. His research focuses on Wnt signaling, cell polarity, and protein palmitoylation in cancer progression.
- Education: B.A. in Biology (1994) and Ph.D. in Molecular, Cell & Developmental Biology (2003) from University of California, Santa Barbara
- Contact: 754 Biomedical Research Building II/III, 421 Curie Boulevard, Philadelphia, PA 19104-6160
Key research areas include:
- Non-canonical Wnt5a signaling in melanoma metastasis
- APT1-mediated depalmitoylation of MCAM
- DHHC20-regulated EGFR activation in cancer
- Lipid synthesis control of Wnt5a production
- Polarized calcium gradients in cell migration
His recent publications highlight novel mechanisms connecting protein palmitoylation to cancer signaling and therapy resistance. The lab employs biochemical and live-cell imaging approaches to study these processes.
۰مقاله منتشرشده
