معرفی
Erhard Bieberich is a Professor in the Department of Physiology at the University of Kentucky, with affiliations to the Markey Cancer Center, Molecular and Cellular Oncology Research Program, and Neuroscience Research Priority Area. His research bridges sphingolipid metabolism, neurodegenerative diseases, and cancer biology, focusing on ceramide signaling and its implications in health and disease.
Education:
- Doctor of Philosophy, University of Cologne (1990)
- Master of Science, University of Cologne (1986)
- Post-Doctoral Fellowship, German Research Foundation, Bonn (1996)
Research Interests center on sphingolipid biochemistry, ceramide-mediated signaling, and their roles in Alzheimer's disease, stem cell regulation, and multiple myeloma. His work explores how neutral sphingomyelinase-2 (nSMase-2) influences extracellular vesicle communication and mitochondrial homeostasis.
Selected Research Trends from recent publications include:
- Ceramide regulation in neurodegenerative disease via small extracellular vesicles
- Role of nSMase2 in nervous system development and aging
- Lipid metabolism in multiple myeloma through ACOX1-MET/IGF1R axis
- Mechanisms of plasma membrane ceramide homeostasis
- Transcriptional regulation of sphingolipid pathways in aging.
Scientific Awards
- Travel Award (American Society for Neurochemistry, 1997)
- Outstanding Young Basic Science Faculty Award (2004)
- Distinguished Teacher Award (2009)
- Distinguished Research Award (2013)
Current Projects include NIH-funded studies on nSMase-2 in hepatic steatosis, ceramide in neurodegeneration, and lipid metabolism in multiple myeloma. He also contributes to the University of Kentucky Alzheimer's Disease Research Center as a former collaborator.
