En Huang

En Huang is an Associate Professor at the University of Arkansas for Medical Sciences within the College of Public Health's Environmental Health Sciences department. His research focuses on antimicrobial resistance mechanisms in pathogens, particularly carbapenem-resistant and Gram-negative bacteria, and the development of novel lipopeptides and phage therapies for infection control.

• Institution: University of Arkansas for Medical Sciences
• Department: Environmental Health Sciences
• Academic Rank: Associate Professor

Huang's work spans Mechanisms of Antibiotic Resistance (e.g., cefiderocol nonsusceptibility, SHV β-lactamases, OmpK35 porin loss) and Antimicrobial Development (e.g., paenipeptins, paenibacillin, brevibacillin). He investigates Genomic Surveillance of pathogens, Food Safety risks from antibiotic-resistant bacteria, and Environmental Health implications of resistance transmission.

His recent publications highlight trends in combating carbapenem-resistant pathogens via insertion sequence analysis, lipopeptide engineering for membrane disruption, and Nanopore Sequencing for DNA modification detection. Collaborations with teams like Jun, Lowry, and Moon reflect interdisciplinary approaches.

Scientific Awards (not explicitly listed but inferred from NIH/NIFA funding):
• NIH/NIAID R01AI175440: Mechanisms of cefiderocol resistance (2024-2029)
• NIFA AI169138: Assessment of antibiotic resistance in vegetables (2022-2026)
• NIH/NIAID R21AI146693: Paenipeptins for antibiotic synergy (2019-2022)

Huang leads studies on antimicrobial potentiation and genomic analysis, with applications in food safety, clinical infections, and environmental health. His lab employs techniques like Nanopore Sequencing and Bacteriophage Therapy to address antibiotic resistance across diverse ecosystems.