Emily E Blythe

Emily E Blythe is an Assistant Professor in the Department of Genetics, Cell Biology and Development at the University of Minnesota's College of Biological Sciences. Her research focuses on GPCR signaling mechanisms, particularly endomembrane dynamics and cAMP signaling pathways.

• Current NIH-funded project: Mechanisms of spatiotemporal signaling by GPCRs (2025-2028)
• Key research themes: Protein trafficking, myosin interactions, and non-canonical signaling pathways

Recent publications highlight her work on:

• Arrestin-independent GPCR internalization via Myosin VI
• Proteomic profiling of opioid receptors
• β-Arrestin-independent endosomal cAMP signaling
• Macrocyclic peptide-based modulation of G-protein signaling