معرفی
Emanuel Rosonina is an Associate Professor in the Department of Biology at York University's Faculty of Science. He specializes in studying the molecular mechanisms controlling gene expression in eukaryotic cells, particularly focusing on RNA Polymerase II transcription and the role of SUMO post-translational modifications. His research employs budding yeast as a model organism, combining molecular biology, biochemistry, yeast genetics, and genomics technologies like ChIP-seq.
Key research areas include (1) understanding how transcription factors and general transcription machinery regulate gene activation and reinitiation, and (2) investigating how SUMOylation dynamically alters gene expression under normal and stress conditions. Current funding includes NSERC Discovery Grant and CIHR Operating Grant. The Rosonina Lab is part of York University's Keele, Glendon, and Markham campuses. Contact: rosonina@yorku.ca | Phone: (416) 736-2100 x44702.
Scientific contributions span over 20 peer-reviewed publications since 2000, addressing topics like chromatin remodeling, transcription factor specificity, and stress-induced epigenetic changes. His work bridges fundamental molecular mechanisms with broader implications for cellular adaptation and disease contexts such as cancer and environmental stress responses.
