Ellen Niederberger

Ellen Niederberger is a Professor at the Institute for Clinical Pharmacology of Goethe University Frankfurt. Her research focuses on elucidating molecular mechanisms of pain and inflammation to identify novel therapeutic drug targets, particularly examining kinase signaling pathways and protein/microRNA regulation in spinal cord and dorsal root ganglia (DRG) after nociceptive stimulation.

• Key Research Areas:
  • Mechanisms of inflammatory/neuropathic pain
  • Role of kinases (IKKepsilon, AMPK) in nociception
  • Epigenetic and molecular regulation in pain models
• Methods:
  • Primary neuron/astrocyte culture
  • Immunohistochemistry, Western Blot, 2D gel electrophoresis
  • In vivo rodent pain models with behavioral analysis