Ellen De Langhe

Ellen De Langhe serves as an Assistant Professor at KU Leuven's Faculty of Medicine within the Department of Development and Regeneration. She is affiliated with the Skeletal Biology and Engineering Research Center and holds membership in the Council of the Faculty of Medicine and the Council of the Department of Development and Regeneration as senior academic staff. Her institutional profile highlights her active research leadership through multiple ongoing projects.

Dr. De Langhe's research concentrates on autoimmune rheumatic diseases with particular emphasis on autoantibody detection, systemic sclerosis, idiopathic inflammatory myopathies, and giant cell arteritis. Her work bridges laboratory science and clinical applications, focusing on diagnostic assay development, occupational exposure triggers, and disease monitoring methodologies. She investigates the complex interplay between genetic predisposition and environmental factors in autoimmune pathogenesis.

Analysis of her recent publications reveals a strong focus on diagnostic innovation in rheumatology, with significant contributions to autoantibody characterization, vasculitis assessment, and dermatomyositis phenotyping. Her research spans basic science (mass spectrometry-based autoantibody detection), clinical studies (validation of disease activity scores), and epidemiological investigations (occupational exposure assessment).

Dr. De Langhe actively leads multiple research projects including as Promotor for 'Systemic sclerosis and occupational silica or solvent exposure' (2020-2025) and 'Anti-MDA5 autoantibodies in Idiopathic Inflammatory Myopathies' (2019-2025), while serving as Co-promotor on several other significant grants focused on autoantibody quantification and novel biomarker identification.

Her teaching portfolio encompasses rheumatology and internal medicine courses including 'Vaardigheden in de reumatologie' (Rheumatology Skills) series and problem-solving modules in internal medicine. She contributes to integrated clinical research and reasoning training for master's students at KU Leuven.