Elisa Oberbeckmann

Elisa Oberbeckmann serves as a Research Group Leader and Junior Professor (Assistant Professor) at the University of Göttingen, with primary research conducted at the Max Planck Institute in Göttingen. Her work focuses on fundamental mechanisms of chromatin dynamics and gene expression regulation, with direct implications for understanding cancer development through dysregulation of genomic processes.

Her core research interests include:

• Molecular functions of ATP-dependent chromatin remodelers
• Nucleosome positioning and genome accessibility
• 3D genome folding mechanisms
• Epigenetic regulation of transcription
• Chromatin reconstitution techniques
• Cancer-related gene expression dysregulation

Dr. Oberbeckmann leads the Chromatin Dynamics research group that pioneered genome-wide chromatin reconstitution using purified proteins, combining innovative biochemical approaches with Next Generation Sequencing to map nucleosome positions. Her team's breakthrough recreation of yeast 3D genome folding, published in a January 2024 press release, provides critical insights into how spatial genome organization regulates gene activity. The group actively investigates how chromatin remodelers interact with transcription factors and epigenetic modifications in controlled chromatin environments to influence disease pathways.