Douglas E. Feldman

Douglas E. Feldman, PhD, is an Assistant Professor of Research Pathology. His research focuses on immunomodulation, DNA modification, and epigenetic mechanisms in cancer and fibrosis. Key areas include immune engineering, viral counter-immune systems, and the role of modified DNA bases in gene regulation. His work intersects stem cell biology, oncology, and inflammatory diseases.

Research interests span topics such as tumor-initiating stem-like cells, immune evasion strategies, and DNA repair pathways. He explores how environmental factors like alcohol and diabetes contribute to cancer stem cell formation. His studies also address viral and bacterial mechanisms that counteract host immune responses, including phage anti-defense genes.

Dr. Feldman’s publications highlight interdisciplinary approaches, combining molecular biology, immunology, and genetics to understand disease mechanisms. He has contributed to understanding the interplay between TLR4, TGF-β, and hypoxia in tumor progression. His lab’s work bridges basic science and translational research in epigenetics, cancer biology, and immune therapy.

No scientific awards are explicitly listed, though his extensive publication record reflects active research contributions. Grants and lab collaborations are not detailed here, but his research themes suggest involvement in collaborative projects addressing complex biological systems.