Douglas C. Noll

Douglas C. Noll is the Ann and Robert H. Lurie Professor of Biomedical Engineering and Professor of Radiology at the University of Michigan. He holds key roles as Co-Director of the Functional MRI Laboratory, Co-Lead of the NeuroImaging Core at the Michigan Alzheimer’s Disease Research Center, and collaborator at the Michigan Institute for Imaging Technology and Translation (MIITT). His affiliations include the Michigan Neuroscience Institute, Center for Computational Medicine and Bioinformatics, and Michigan Concussion Center.

His research focuses on advancing MRI and fMRI technologies to study brain function and neurological disorders. Key projects include rapid image acquisition, artifact elimination, physiological modeling, and MRI-guided therapies like histotripsy. Recent work emphasizes pre-clinical MRI-guided focused ultrasound systems and collaborations with neuroscientists to map brain organization in health and disease.

Notable contributions include developing the Oscillating Steady State Imaging (OSSI) technique, the TOPPE framework for MRI sequence prototyping, and tools like FieldMapNet MRI for off-resonance correction. His lab addresses challenges in high-resolution fMRI, real-time motion compensation, and translational imaging for clinical applications.

Current efforts span improving MRI hardware-software integration, advancing non-invasive brain therapies, and applying machine learning to enhance image reconstruction and artifact correction. Collaborations bridge engineering, neuroscience, and clinical medicine to tackle complex neurological conditions like Alzheimer’s and brain tumors.