Douglas Arnold

Douglas Arnold is a Distinguished James McGill Professor at McGill University, based at The Neuro (Montreal Neurological Institute-Hospital). He serves as Core Faculty for the Brain Imaging Centre (BIC) within the Neuroimaging and Neuroinformatics Research Group, specializing in advanced MRI applications for neurological disorders. His clinical role includes neurology practice with expertise in quantitative imaging biomarkers.

Dr. Arnold's research centers on developing and applying neuroimaging techniques to track pathological evolution in multiple sclerosis and Alzheimer's disease. He investigates gray/white matter changes, lesion dynamics, and therapy effects using magnetization transfer imaging, spectroscopic methods, and voxel-based analysis. His work bridges technical innovation with clinical applications to quantify neurodegeneration and treatment efficacy.

Analysis of his publications reveals consistent focus on multiple sclerosis pathophysiology, particularly demyelination/remyelination processes and cortical pathology. Key methodological contributions include advanced MRI quantification for brain atrophy, lesion evolution, and neuroprotection assessment. His collaborative work spans clinical trials (e.g., rituximab therapy) and technical innovations in imaging analysis.

As an active member of The Neuro's Neuroimaging and Neuroinformatics Research Group, Dr. Arnold contributes to McGill University's neuroscience mission within the McGill University Health Centre. His work supports open science initiatives through data sharing and methodological transparency, advancing both research and clinical practice in neurodegenerative diseases.