Mark Mühlau

Prof. Dr. Mark Mühlau serves as a Professor and Research Group Leader at the Department of Neurology, School of Medicine, Technical University of Munich (TUM). He holds dual affiliations as a full member of the Graduate School of Systemic Neurosciences (GSN) and regular member of the Munich Center for Neurosciences (MCN).

His research centers on voxel-based structural magnetic resonance imaging with primary applications in multiple sclerosis and neurodegenerative disorders. Key methodologies include FLAIR-hyperintense lesion detection and voxel-based morphometry for analyzing gray/white matter interactions. His work bridges clinical neurology with advanced computational neuroimaging techniques to investigate disease progression mechanisms.

Publication analysis (2008-2013) reveals consistent focus on MRI innovation for neurological conditions, particularly multiple sclerosis and Huntington's disease. His studies demonstrate how white-matter lesions drive secondary gray-matter atrophy, while developing automated tools for lesion quantification. This trajectory highlights translational research connecting structural brain changes to clinical manifestations.

Prof. Mühlau leads a dedicated research group at TUM's Neurological Clinic and Polyclinic (Klinikum rechts der Isar), operating within specialized neuroimaging facilities focused on advancing diagnostic precision for neurodegenerative conditions.