Domenic Burger

Roles & Affiliation: Domenic Burger is a current member of EPFL affiliated with the LBEM (Laboratory) unit, focusing on structural biology and neurodegenerative diseases. His research combines advanced microscopy techniques with molecular pathology analysis.

Education: Holds a Doctoral degree from EPFL, as reflected in his thesis titled 'Disentangling Multiple System Atrophy' (2024).

Research Interests: Specializes in alpha-synuclein fibril structures, mechanisms of Multiple System Atrophy (MSA), and correlative light-electron microscopy (CLEM). His work bridges ultrastructural analysis with disease progression studies, particularly in neurological disorders.

Publications: Recent work includes advancements in CLEM protocols for human brain tissue and high-resolution structural analysis of synthetic α-synuclein fibrils. These studies explore fibril transmission in animal models and their implications for prion-like disease mechanisms.

Awards & Grants: No specific awards mentioned, but research is supported by institutions like the Swiss National Science Foundation and EMBO.

Advising & Labs: Works within the LBEM unit at EPFL, collaborating with teams such as Chimie et Biologie des Membranes et des Nanoobjects. His lab focuses on integrating cryo-EM and correlative microscopy to study neurodegenerative pathology.