معرفی
Dinesh Jaishankar, PhD is a Research Assistant Professor in the Department of Surgery (Organ Transplantation) at Northwestern University's Feinberg School of Medicine. He leads research in transplant immunobiology, focusing on improving organ preservation, reducing transplant rejection, and understanding viral pathogenesis. His work integrates bioengineering, nanotechnology, and immunology to address clinical challenges in transplantation and infectious diseases.
Education: PhD from the University of Illinois (2017).
Research Focus: Dr. Jaishankar investigates endothelial cell biology in ischemia-reperfusion injury, immunomodulatory therapies for transplant survival, and novel antiviral strategies targeting herpesviruses. His lab develops nanotherapeutics for ex vivo organ perfusion and explores biomarkers for immunotherapy response prediction. Key areas include ER stress pathways in kidney injury, skin infiltrate analysis for checkpoint inhibitors, and heparan sulfate-driven viral entry mechanisms.
Recent Trends in Publications: Recent work emphasizes translational applications like bioengineered ACE2 proteins for kidney preservation and autophagy modulation strategies. He also explores predictive biomarkers (e.g., ERK1/2 phosphorylation in glioblastoma immunotherapy) and cellular stress responses in transplantation.
Affiliations: He is affiliated with the Comprehensive Transplant Immunobiology Laboratory, Center for Human Immunobiology, Comprehensive Transplant Center, and Northwestern University Clinical and Translational Sciences Institute (NUCATS). No external professional relationships were reported for 2024.
Labs/Teams: Directs research in the Comprehensive Transplant Immunobiology Laboratory, focusing on preclinical models of organ transplantation and viral infection interventions.
