معرفی
Professor Dimitris Lagos is a faculty member at the Hull York Medical School under the University of York. He holds the role of Professor of Immunology and serves as the Director of Research, leading the Departmental Research Committee. His academic career includes prior appointments as Lecturer, Senior Lecturer, and Reader at Hull York Medical School.
Professor Lagos' research focuses on RNA Biology and RNA Medicine, specifically investigating RNA-driven immune gene regulation in infection and cancer. His group explores transcriptome instability in cancer, sexual dimorphism in lymphocytes, and circulating non-coding RNAs as disease biomarkers. He utilizes advanced transcriptomics platforms like long-read RNA sequencing and spatial omics for discovery, with pharmacological RNA targeting as a therapeutic strategy.
His recent publications highlight trends in immune checkpoint regulation (e.g., PD-L1, IDO1), Cancer Immunology, and RNA-based biomarkers for disease prognosis. He leads the MANIFEST immuno-oncology consortium and collaborates with Oxford Nanopore Technologies. His group has historically spearheaded molecular pathology themes in global infectious disease consortia, including the UK Coronavirus Immunology Consortium.
Professor Lagos is funded by Cancer Research UK and UKRI (MRC and BBSRC). He supervises postgraduate students Mags Gwynne, Ali Deghany, Charlotte Booth, and Molly Cartwright. His work bridges gene regulation, RNA Medicine, and Immunology, emphasizing translational applications.
