Brian D Brown

Dr. Brian D Brown is a Professor at the Icahn School of Medicine at Mount Sinai, where he serves as Vice Chair of Immunology & Immunotherapy, Director of the Icahn Genomics Institute (IGI), and Associate Director of the Precision Immunology Institute (PrIISM). His research bridges immunology, molecular biology, and biotechnology, with a focus on cancer immunology and therapeutic gene regulation.

• BSc, University of Guelph
• PhD, Queen's University
• Postdoctoral Fellowship, San Raffaele Scientific Institute, Italy

Dr. Brown's work centers on understanding immune system control mechanisms to develop therapies for cancer and viral infections. His lab pioneered technologies like the Jedi system for T cell-tissue interaction analysis and advanced gene editing platforms. Research spans genomics, RNA biology, dendritic cell regulation, and innate immunity.

The lab's recent publications highlight computational immunology, single-cell RNA analysis, and miRNA-driven gene regulation, with applications in cancer immunotherapy, viral vaccines, and genetic disease.

Dr. Brown's laboratory employs a multidisciplinary approach to biomedical challenges, integrating experimental therapeutics, molecular engineering, and translational research to enhance immune responses against diseases.